Virginiamycin Powder

virginiamycin intensive poultry farming growth promoter. virginiamycin poultry veterinary medicine virginiamycin is intended for use in broiler chickens for the treatment of necrotic enteritis, a common frequently fatal gastrointestinal disease in poultry caused by toxigenic strains of Clostridium perfringens.

Virginiamycin has also been used as a growth promoter. The use of virginiamycin as a feed additive in pigs and poultry can result in the selection of resistance in faecal enterococci with cross-resistance to quinuspristin/dalfopristin, which has been used in human medicine to treat VRE infections.

In veterinary medicine virginiamycin is intended for use in broiler chickens for the treatment of necrotic enteritis, a common frequently fatal gastrointestinal disease in poultry caused by toxigenic strains of Clostridium perfringens

Virginiamycin is a peptolide antibiotic consisting of a predominant M fraction (C28H35N3O7) and the lesser S fraction (C43H49NO10). The S and M fractions have bacteriostatic and bactericidal activities when they are used separately and together, respectively. Virginiamycin is not known to have synergistic activity with other classes of antibiotics.

Virginiamycin inhibits protein synthesis by binding to the 23S ribosomal subunit and blocking the translation process, with no effect on transcription. It is not commonly used to treat bacterial infections in domestic animals despite possessing a broad-spectrum antimicrobial activity. Most often it is used as a feed-additive formulation for growth promotion in animals such as swine, turkey, and broiler chickens.